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Disabling Medical Conditions

Medical Conditions and Social Security Disability

The disability decision turns on medically determinable impairments, functional limitations, duration, and ability to sustain work.

Physical and mental impairments

Social Security evaluates limitations, duration, and vocational effect—not diagnosis alone.

A person may have one severe condition or a combination of physical and mental impairments. The claim should address all medically determinable impairments because their combined effect may be greater than any diagnosis considered separately.

Musculoskeletal conditions

Spine disorders, arthritis, joint disease, injuries, chronic pain, and related limitations in lifting, walking, standing, sitting, reaching, or handling.

Cardiac and vascular disease

Heart failure, coronary disease, arrhythmias, vascular disease, edema, fatigue, and exertional intolerance.

Pulmonary disease

COPD, asthma, interstitial disease, oxygen dependence, sleep-related breathing disorders, and environmental restrictions.

Neurological disorders

Seizures, neuropathy, multiple sclerosis, stroke effects, headaches, tremors, and cognitive changes.

Mental health conditions

Depression, anxiety, trauma-related disorders, bipolar disorder, psychotic disorders, and limits in concentration, interaction, or adaptation.

Cancer and treatment effects

Active disease, surgery, chemotherapy, radiation, recurrence risk, fatigue, neuropathy, pain, and recovery periods.

Endocrine and immune disorders

Diabetes complications, autoimmune disease, inflammatory conditions, and systemic symptoms.

Kidney, liver, and gastrointestinal disease

Dialysis, organ dysfunction, ostomies, frequent treatment, pain, fatigue, and unpredictable symptoms.

Multiple impairments

The combined impact of obesity, pain, medication, mental symptoms, fatigue, and other conditions should be evaluated together.

Listing-level disability and residual functional capacity.

Some claims meet or medically equal criteria in Social Security’s Listing of Impairments. Many approved claims do not. When a listing is not met, SSA assesses residual functional capacity and asks whether the claimant can perform past relevant work or adjust to other work.

That is why the record should describe what a claimant can do repeatedly, reliably, and on a sustained basis—not merely what can be done once on a good day.

Official sources and further reading

Links open official government resources. This page provides general information and is not a substitute for advice about an individual claim.

Written and reviewed by Joel J. HumphriesSocial Security disability attorney · Licensed in Georgia and North Carolina · Focused on disability law since 2011
Last reviewedJuly 28, 2026

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